Brainwaves from human participants activated a tiny light which had been implanted in mice.
This LED then activated light-sensitive genes which had been genetically engineered to respond in this way.
The authors report that the technology could one day be used to control pain management or pre-empt epileptic seizures.
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Senior author of the work, Martin Fussenegger at ETH Zurich in Switzerland, said it was a huge step forward.
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